20 beste Stellen als project & service in graz, st – aktuell auf Personalsuche

Paid Diploma / Master's Thesis - Advancing the capabilities of optical coherence tomography to measure porosity
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Paid Diploma / Master's Thesis - Advancing the capabilities of optical coherence tomography to measure porosity

Research Center Pharmaceutical Engineering GmbH
Graz, ST

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Master
Bachelor

Vollständige Stellenbeschreibung

Paid Diploma / Master's Thesis

Advancing the capabilities of optical coherence tomography to measure porosity
Ref. No. DA188

To dedicated students of process engineering, chemical and pharmaceutical engineering, or, experimental/applied physics.

OBJECTIVE

The in-line monitoring of product porosity is highly relevant in different industries, as the porosity defines various product characteristics. In the pharmaceutical industry, the porosity of granules, an important intermediate, governs their compaction properties, flowability, and dissolution performance, hence impacting the quality of the final drug product. To enable the control of the porosity, an accurate and robust in-line monitoring technology is highly desirable.

Optical coherence tomography (OCT) bears the potential to become such a technology, with the first applications to tablets already realized. However, the expansion to other products requires further development of the imaging technology and the subsequent signal and image processing steps. The goal is to develop a robust process analytical technology (PAT) based on first principles, providing a method with high reliability and explainability, meeting the requirements in the pharmaceutical industry.

The thesis will include considerations of the optical and mechanical design of the OCT hardware and lay a strong focus on signal and image processing. Experimental trials at RCPE’s lab and pilot plant facilities will be an inherent part, providing data for development and verification of the technology. Hence, existing knowledge in optics and programming skills, as well as experience in planning experimental trials, are clear advantages.

WITHIN THE FRAMEWORK OF THIS DIPLOMA / MASTER’S THESIS WE OFFER THE FOLLOWING:

Extensive participation in a top-level and industrially relevant research project in an international environment
Working with class-leading equipment (Phylon OSeeT)
Supervised training in the task
Assistance of experienced staff with the implementation of innovative ideas
Access to highly modern infrastructure on campus of Graz University of Technology
Assistance with the publication of results

FINANCING

Compensation on the basis of a service contract

If you are interested in writing your thesis at the interface between university research and industry/ business and to contribute to the optimization of product and process development in the pharmaceutical industry, please apply directly via our website.

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Erweiterte Suche

project & service Jobs in graz, st

Paid Diploma / Master's Thesis - Advancing the capabilities of optical coherence tomography to measure porosity

Projektmitarbeiter:in Wasserstoff

Paid Diploma / Master's Thesis - Strategic and economic assessment of a new pharmaceutical cleaning business line at RCPE

Executive Director of the European Centre for Modern Languages (ECML)

Paid Diploma / Master's Thesis - Confromer generation of flexible multi-domain proteins - towards more realistic models of solution structures

Working Student Change & Configuration Management (m/f/d)

Paid Diploma / Master's Thesis - Evaluation of spray models in coupled simulations

Paid Diploma / Master's Thesis - Modeling and process control for a continuous biopharmaceutical production line

Sales Project Specialist - Customer Service (m/w/d)

Paid Diploma / Master's Thesis - AI-driven self-optimizing DEM simulations

Paid Diploma / Master's Thesis - Co-processed systems for inhalation - biological effects in the lung

Paid Diploma / Master's Thesis - Properties organic molecular crystals from molecular simulation - towards prediction of powder properties and parametrization of DEM models from first principles

Projektleiter:in Wasserstoff

Paid Diploma / Master's Thesis - Spray Drying: A CFD based approach to scaling

Automation Technician (m/f/d)

Service Delivery Manager m/f/d

Project Controller - Customer Service (m/w/d)

Field Service Engineer

Radar Component Verification Specialist (f/m/div)

User Operation Manager of East EU

Ich möchte aktuelle Job-E-Mails für Stellen als project & service in graz, st erhalten

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